• Mark Twain Brewing Company

    422 North Main Street
    Hannibal, MO 63401


    Call Us
    (573) 406-1300

    Mon: 11:00AM-8:00PM
    Tue: 11:00AM-8:00PM
    Wed: 11:00AM-8:00PM
    Thu: 11:00AM-8:00PM
    Fri: 11:00AM-10:00PM
    Sat: 11:00AM-10:00PM
    Sun: 11:00AM-8:00PM

Find a Brewery in Hannibal, MO

Try our locally brewed craft beer

Thank you for visiting the website of Mark Twain Brewing Company. Our brewery in Hannibal, MO is known throughout the region for the unique craft beer we brew. Stop by our brew pub today to grab a bite to eat and find your new favorite beer.

Call 573-406-1300 now to learn about our specials and upcoming events.

Please use the form on this page to email us.

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